ACD

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity.

The following ACD reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ACD Antibodies

ACD Proteins

ACD Antibodies

ACD Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA839289LA01HU	ACD Antibody	Human, Mouse	ELISA, WB
CSB-PA839289LC01HU	ACD Antibody, FITC conjugated	Human

ACD Proteins

ACD Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP839289HU CSB-EP839289HU CSB-BP839289HU CSB-MP839289HU CSB-EP839289HU-B	Recombinant Human Adrenocortical dysplasia protein homolog (ACD)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ACD Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP677933RA CSB-EP677933RA CSB-BP677933RA CSB-MP677933RA CSB-EP677933RA-B	Recombinant Rat Adrenocortical dysplasia protein homolog (Acd)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ACD Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP682726MO CSB-EP682726MO CSB-BP682726MO CSB-MP682726MO CSB-EP682726MO-B	Recombinant Mouse Adrenocortical dysplasia protein (Acd)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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