CCL23

CCL23, also known as MIP-3 or MPIF-1, is a chemokine ligand predominantly produced by macrophages and dendritic cells in tissues like the lung, liver, and pancreas. By binding to the CCR1 receptor, CCL23 activates and directs the migration of monocytes, macrophages, and T lymphocytes to inflammatory or damaged sites, playing a crucial role in immune and inflammatory responses. It has a broad biological impact, participating in various pathological processes, including autoimmune diseases, infections, and cancer. CCL23 is a central factor in immune regulation and the pathogenesis of diseases.