EZH2

EZH2, recognized as the enhancer of zeste homolog 2, is a histone methyltransferase encoded by the EZH2 gene and a key component of the PRC2 (polycomb repressive complex 2) complex. This enzyme plays a role in gene silencing through the methylation of histone H3 at lysine 27, a modification that can lead to the repression of gene expression. EZH2 influences critical biological processes such as cell proliferation, differentiation, development, and the onset of cancer. An overabundance of EZH2 is linked to an unfavorable prognosis in certain cancers, including lymphomas and epithelial tumors, underscoring its significance as a potential target for therapeutic intervention in cancer treatment

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

EZH2 Recombinant Monoclonal Antibody(CSB-RA218051A0HU)

Validated Data

IHC image of CSB-RA218051A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

The following EZH2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

EZH2 Antibodies

EZH2 Proteins

EZH2 Antibodies

EZH2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA923709XA01DIL	ezh2 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

EZH2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA007913GA01HU	EZH2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA613606ESR2HU	EZH2 Antibody	Human, Mouse	ELISA, WB
CSB-PA761728	EZH2 Antibody	Human,Mouse	ELISA,WB
CSB-PA934125	EZH2 Antibody	Human,Mouse	ELISA,WB
CSB-RA218051A0HU	EZH2 Recombinant Monoclonal Antibody	Human	ELISA, IHC
CSB-RA942183A0HU	EZH2 Recombinant Monoclonal Antibody	Human	ELISA, IHC

EZH2 Proteins

EZH2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP689938MOV CSB-EP689938MOV CSB-BP689938MOV CSB-MP689938MOV CSB-EP689938MOV-B	Recombinant Macaca fascicularis Histone-lysine N-methyltransferase EZH2 (EZH2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

EZH2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP613606HU CSB-EP613606HU CSB-BP613606HU CSB-MP613606HU CSB-EP613606HU-B	Recombinant Human Histone-lysine N-methyltransferase EZH2 (EZH2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP613606HU	Recombinant Human Histone-lysine N-methyltransferase EZH2 (EZH2)	Yeast

EZH2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-YP636758XBF CSB-EP636758XBF CSB-BP636758XBF CSB-MP636758XBF CSB-EP636758XBF-B	Recombinant Xenopus tropicalis Histone-lysine N-methyltransferase EZH2 (ezh2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

EZH2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP723402MO CSB-EP723402MO CSB-BP723402MO CSB-MP723402MO CSB-EP723402MO-B	Recombinant Mouse Histone-lysine N-methyltransferase EZH2 (Ezh2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP723402MO1	Recombinant Mouse Histone-lysine N-methyltransferase EZH2 (Ezh2), partial	E.coli

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EZH2

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