GPR161

G-protein coupled receptor 161 is a protein in humans that is encoded by GPR161 gene. Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

The following GPR161 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GPR161 Antibodies

GPR161 Proteins

GPR161 Antibodies

GPR161 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA820893XA01DIL	gpr161 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

GPR161 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA04114A0Rb	GPR161 Antibody	Human	ELISA, WB, IF
CSB-PA04114C0Rb	GPR161 Antibody, FITC conjugated	Human
CSB-PA009774GA01HU	GPR161 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-EAP04114	GPR161 Antibody Pair	Human,Rat,Guinea pig,Bovine,Horse,Pig,Dog,Goat,Sheep	S-ELISA

GPR161 Proteins

GPR161 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-CF820893DIL	Recombinant Danio rerio G-protein coupled receptor 161 (gpr161)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP820893DIL1 CSB-EP820893DIL1 CSB-BP820893DIL1 CSB-MP820893DIL1 CSB-EP820893DIL1-B	Recombinant Danio rerio G-protein coupled receptor 161 (gpr161), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPR161 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF836681HU	Recombinant Human G-protein coupled receptor 161 (GPR161)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-RP041144h	Recombinant Human G-protein coupled receptor 161 (GPR161), partial	E.coli
CSB-YP836681HU CSB-EP836681HU CSB-BP836681HU CSB-MP836681HU CSB-EP836681HU-B	Recombinant Human G-protein coupled receptor 161 (GPR161), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP836681HUe0	Recombinant Human G-protein coupled receptor 161(GPR161), partial	E.coli

GPR161 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF009774BO	Recombinant Bovine G protein-coupled receptor 161 (GPR161)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP009774BO1 CSB-EP009774BO1 CSB-BP009774BO1 CSB-MP009774BO1 CSB-EP009774BO1-B	Recombinant Bovine G protein-coupled receptor 161 (GPR161), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPR161 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-CF009774XBF	Recombinant Xenopus tropicalis G-protein coupled receptor 161 (gpr161)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP009774XBF1 CSB-EP009774XBF1 CSB-BP009774XBF1 CSB-MP009774XBF1 CSB-EP009774XBF1-B	Recombinant Xenopus tropicalis G-protein coupled receptor 161 (gpr161), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPR161 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF009774MO	Recombinant Mouse G-protein coupled receptor 161 (Gpr161)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP009774MO1 CSB-EP009774MO1 CSB-BP009774MO1 CSB-MP009774MO1 CSB-EP009774MO1-B	Recombinant Mouse G-protein coupled receptor 161 (Gpr161), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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