HAVCR2

HAVCR2, also known as TIM-3 (T-cell immunoglobulin domain and mucin domain-3), is a transmembrane protein predominantly expressed on T cells. It interacts with ligands such as phosphatase CD244 and phosphatidylserine (PS), modulating immune responses and serving as an inhibitory receptor in T cell activity regulation. HAVCR2's role extends to autoimmune diseases, infectious diseases, tumor immune surveillance, and immune escape, marking it as an inhibitory molecule in adaptive immunity. Its expression changes in tumors suggest potential as a target in immunotherapy research.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

HAVCR2 Recombinant Monoclonal Antibody(CSB-RA010145MA1HU)

Validated Data

Immunofluorescence staining of Hela cell with CSB-RA010145MA1HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).

Human Hepatitis A virus cellular receptor 2(HAVCR2) ELISA kit(CSB-EL010145HU)

Validated Data

Code: CSB-EL010145HU

Size: 96T,5×96T,10×96T

Sensitivity: 11.75 pg/mL

Detection Range: 47 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following HAVCR2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HAVCR2 Antibodies

HAVCR2 Proteins

HAVCR2 ELISA Kits

HAVCR2 Antibodies

HAVCR2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA010145GA01HU	HAVCR2 Antibody	Human	ELISA,WB
CSB-PA010145LC01HU	HAVCR2 Antibody, FITC conjugated	Human
CSB-PA010145LA01HU	HAVCR2 Antibody	Human	ELISA, IF
CSB-PA010145LD01HU	HAVCR2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA010145LB01HU	HAVCR2 Antibody, HRP conjugated	Human	ELISA
CSB-EAP010145	HAVCR2 Antibody Pair	Human,Guinea pig,Bovine,Horse,Pig,Dog,Chicken,Goat	S-ELISA
CSB-RA010145MA1HU	HAVCR2 Recombinant Monoclonal Antibody	Human	ELISA, IF
CSB-RA010145MB11HU	HAVCR2 (TQB-2618 Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB1HU	HAVCR2 (verzistobart Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB2HU	HAVCR2 (BC-3402 Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB3HU	HAVCR2 (BMS-986258 Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB4HU	HAVCR2 (Cobolimab Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB5HU	HAVCR2 (LBL-003 Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB6HU	HAVCR2 (LY-3321367 Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB7HU	HAVCR2 (NB-002 Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB8HU	HAVCR2 (Sabatolimab Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB9HU	HAVCR2 (Surzebiclimab Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA010145MB10HU	HAVCR2 (Sym-023 Biosimilar) Recombinant Monoclonal Antibody	Human

HAVCR2 Proteins

HAVCR2 Proteins for

Code	Product Name	Source
CSB-MP010145HU1d7-CS	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	Mammalian cell
CSB-MP010145HU1d7-CS-LX	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	Mammalian cell

HAVCR2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP010145HU	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	Yeast
CSB-EP010145HU	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	E.coli
CSB-YP010145HU CSB-EP010145HU CSB-BP010145HU CSB-MP010145HU CSB-EP010145HU-B	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP005281HU	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (Active)	Mammalian cell
CSB-AP005291HU	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (Active)	Mammalian cell
CSB-MP010145HU	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	Mammalian cell
CSB-MP010145HU1	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	Mammalian cell
CSB-MP010145HU1d7	Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial	Mammalian cell

HAVCR2 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP010145RA CSB-EP010145RA CSB-BP010145RA CSB-MP010145RA CSB-EP010145RA-B	Recombinant Rat Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HAVCR2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP840881MO CSB-EP840881MO CSB-BP840881MO CSB-MP840881MO CSB-EP840881MO-B	Recombinant Mouse Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP005341MO	Recombinant Mouse Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial (Active)	Mammalian cell

HAVCR2 ELISA Kit

HAVCR2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL010145HU	Human Hepatitis A virus cellular receptor 2(HAVCR2) ELISA kit	serum, plasma, tissue homogenates	11.75 pg/mL

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HAVCR2

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