KIR3DL3

KIR3DL3, also known as Killer cell immunoglobulin-like receptor 3DL3, is a protein encoded by the KIR3DL3 gene. It is sometimes referred to as CD158z. The exact mechanism of KIR3DL3 remains unclear, but it is thought to be involved in modulating the activity of immune cells, particularly natural killer cells. It may interact with specific ligands to regulate immune responses.
Regarding its associations, abnormal KIR3DL3 expression has been linked to certain autoimmune and infectious diseases. In terms of drug development, research is in the early stages. Scientists are exploring its potential as a target for immunotherapies to enhance immune - mediated disease control.