RUBCN

Run domain Beclin-1-interacting and cysteine-rich domain-containing protein is a protein in humans that is encoded by RUBCN gene. Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation

The following RUBCN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

RUBCN Antibodies

RUBCN Proteins

RUBCN Antibodies

RUBCN Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA856415LA01HU	RUBCN Antibody	Human	ELISA, IHC
CSB-PA856415LB01HU	RUBCN Antibody, HRP conjugated	Human	ELISA
CSB-PA856415LC01HU	RUBCN Antibody, FITC conjugated	Human
CSB-PA856415LD01HU	RUBCN Antibody, Biotin conjugated	Human	ELISA

RUBCN Proteins

RUBCN Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP856415HU CSB-EP856415HU CSB-BP856415HU CSB-MP856415HU CSB-EP856415HU-B	Recombinant Human Run domain Beclin-1 interacting and cystein-rich containing protein (KIAA0226), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RUBCN Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP767318MO CSB-EP767318MO CSB-BP767318MO CSB-MP767318MO CSB-EP767318MO-B	Recombinant Mouse Run domain Beclin-1 interacting and cystein-rich containing protein (Kiaa0226), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily?Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application