WEE1

WEE1, also known as WEE1 G2 checkpoint kinase, is a key protein involved in cell cycle regulation. It serves as a crucial regulator in the G2/M transition by phosphorylating and inactivating CDK1, thus preventing premature entry into mitosis. WEE1 is implicated in the DNA damage response pathway. Dysregulation of WEE1 has been associated with various cancers, making it an attractive target for cancer therapy.
In drug development, WEE1 inhibitors have shown promise in pre - clinical and clinical studies. These inhibitors aim to disrupt the protective mechanism of cancer cells with DNA damage, leading to enhanced cell death. Clinical trials are ongoing to evaluate the efficacy and safety of WEE1 - targeted therapies in different cancer types, offering new hope for cancer patients.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The following WEE1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

WEE1 Antibodies

WEE1 Proteins

WEE1 Antibodies

WEE1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA062918	Phospho-WEE1 (Ser642) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA060083	Phospho-WEE1 (S642) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA060084	Phospho-WEE1 (S53) Antibody	Human,Mouse,Rat	IHC, ELISA
CSB-PA060085	WEE1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA16059A0Rb	WEE1 Antibody	Human	ELISA
CSB-PA16059B0Rb	WEE1 Antibody, HRP conjugated	Human	ELISA
CSB-PA16059C0Rb	WEE1 Antibody, FITC conjugated	Human
CSB-PA16059D0Rb	WEE1 Antibody, Biotin conjugated	Human	ELISA

WEE1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA811852XA01DOA	WEE1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

WEE1 Antibodies for Oryza sativa subsp. japonica (Rice)

Code	Product Name	Species Reactivity	Application
CSB-PA751135XA01OFG	WEE1 Antibody	Oryza sativa subsp. japonica (Rice)	ELISA, WB (ensure identification of antigen)

WEE1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA357135XA01SXV	wee1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

WEE1 Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA026084XA01DLU	Wee1 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

WEE1 Proteins

WEE1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP723610RA CSB-EP723610RA CSB-BP723610RA CSB-MP723610RA CSB-EP723610RA-B	Recombinant Rat Wee1-like protein kinase (Wee1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WEE1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP026084HU CSB-EP026084HU CSB-BP026084HU CSB-MP026084HU CSB-EP026084HU-B	Recombinant Human Wee1-like protein kinase (WEE1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP026084HU	Recombinant Human Wee1-like protein kinase (WEE1)	E.coli
CSB-EP026084HUc7	Recombinant Human Wee1-like protein kinase (WEE1)	E.coli

WEE1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP811852DOA CSB-EP811852DOA CSB-BP811852DOA CSB-MP811852DOA CSB-EP811852DOA-B	Recombinant Arabidopsis thaliana Wee1-like protein kinase (WEE1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WEE1 Proteins for Oryza sativa subsp. japonica (Rice)

Code	Product Name	Source
CSB-YP751135OFG CSB-EP751135OFG CSB-BP751135OFG CSB-MP751135OFG CSB-EP751135OFG-B	Recombinant Oryza sativa subsp. japonica Wee1-like protein kinase (WEE1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WEE1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP357135SXV CSB-EP357135SXV CSB-BP357135SXV CSB-MP357135SXV CSB-EP357135SXV-B	Recombinant Schizosaccharomyces pombe Mitosis inhibitor protein kinase wee1 (wee1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WEE1 Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP026084DLU CSB-EP026084DLU CSB-BP026084DLU CSB-MP026084DLU CSB-EP026084DLU-B	Recombinant Drosophila melanogaster Wee1-like protein kinase (wee)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WEE1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP026084MO CSB-EP026084MO CSB-BP026084MO CSB-MP026084MO CSB-EP026084MO-B	Recombinant Mouse Wee1-like protein kinase (Wee1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP026084MO	Recombinant Mouse Wee1-like protein kinase (Wee1)	E.coli

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