ftz-f1 Antibody

Code: CSB-PA339334XA01DLU

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20μl50μl100μl

US$83

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Application: ELISA, WB

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Product Details
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Target Background

Product Details

Uniprot NO.

P33244

Target Names

ftz-f1

Alternative Names

Nuclear hormone receptor FTZ-F1 (FTZ-F1 alpha) (Nuclear receptor subfamily 5 group A member 3) ftz-f1 NR5A3 CG4059

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) ftz-f1 protein (790-1027aa )

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Protein G

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot
Positive WB detected in Recombinant protein
All lanes: ftz-f1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 30 kDa
Observed band size: 30 kDa

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Target Background

Function(From Uniprot)

Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'-YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand.

Gene References into Functions

the alpha6 helix is dynamic in solution when Ftz-F1 is bound to the LxxLL motif of its cofactor Ftz, undergoing motions on the fast (picosecond to nanosecond) as well as slow (microsecond to millisecond) time scales. PMID:29547262
a novel ecdysone-dependent enhancer in the intron of ftz-f1 gene PMID:28726107
Comparative analysis of enhancers containing Ftz/Ftz-F1 binding sites that were or were not bona fide targets in vivo suggested that GAF negatively regulates enhancers that contain Ftz/Ftz-F1 binding sites but are not actually utilized. PMID:27723822
dATAC histone acetyltransferase complex is indispensable for the regulation of expression and probably for the stabilization of Ftz-F1, the main transcription regulator of Halloween genes. PMID:25959239
betaFTZ-F1 is expressed in most cells at the late pupal stage, under the control of ecdysteroids and plays important roles during pupal development. PMID:24611773
functional equivalence of ftz-f1 orthologs in these sensitive in vivo assays argues against specific activating ligands for NR5A family members PMID:23340581
ssFTZ-F1 is required for fat-body remodeling in Drosophila PMID:21978772
betaFTZ-F1 is a regulator for temporal gene expression at the onset of metamorphosis PMID:12392575
betaFTZ-F1 plays a role in regulating ecdysteroid titers during post-embryonic developmentby regulating Phantom protein and Disembodied protein expression. PMID:15936331
EDG84A gene encoding pupal cuticle protein is one of the targets of ecdysteroid-inducible transcription factor betaFTZ-F1; betaFTZ-F1 is expressed in almost all tissues. PMID:16025347
Serves as a molecular sign to guide the recruitment of ecdysone receptor/Ultraspiracle/FISC to 20-hydroxyecdysone-inducible target promoters. PMID:17015464
propose that pair-rule genes, exemplified by Ftz/Ftz-F1, promote segmentation by acting at different hierarchical levels, regulating segmentation and regulatory genes PMID:19679121
The Ftz-F1 DNA binding domain interacts strongly with Ftz and dramatically facilitates the binding of Ftz to target DNA. PMID:11520662