kif7 Antibody

Code: CSB-PA704511XA01DIL
Size:
0.1ml
0.1ml1ml
US$Enquire
Quantity:
Species Reactivity: Danio rerio (Zebrafish) (Brachydanio rerio)
Raised in: Rabbit
Application: ELISA, WB (ensure identification of antigen)
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Product Details

Uniprot NO.
Target Names
kif7
Alternative Names
kif7 antibody; cos2Kinesin-like protein kif7 antibody; Kinesin-like protein costal2 antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) kif7 protein
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Lead Time
Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Acts downstream of smo as an intracellular repressor of hedgehog signaling pathway, mainly through the suppression of gli1 activity. This negative regulatory effect is enhanced in conjunction with the suppressor of fused (sufu) protein. Positively regulates gli2a activity by promoting its dissociation from sufu. Involved in the regulation of microtubular dynamics.
Gene References into Functions
  1. both osm-3/kif17 and cos2/kif7 have comparable outer segment developmental delays, although through independent mechanisms. PMID:28341548
  2. We show that Kif7 interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 in Drosophila PMID:24339784
  3. zebrafish Costal2 acts as an intracellular repressor of signal transduction PMID:15647323

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Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, cilium.
Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, KIF27 subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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