Tk Antibody

Code: CSB-PA892843XA01DLU

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

Q9VGE8

Target Names

Alternative Names

Tk antibody; CG14734 antibody; Tachykinins antibody; dTk) [Cleaved into: Tachykinin-related peptide 1 antibody; TK-1 antibody; dTK-1 antibody; APTSSFIGMR-amide); Tachykinin-associated peptide 1 antibody; TAP1 antibody; DEEHDTSEGNWLGSGPDPLDYADEEADSSYAEN-amide); Tachykinin-related peptide 2 antibody; TK-2 antibody; dTK-2 antibody; APLAFVGLR-amide); Tachykinin-associated peptide 2 antibody; TAP2 antibody; FIPINNRLSDVLQSLEEERLRDSLLQDFFDRVAGRDGSAV-amide); Tachykinin-related peptide 3 antibody; TK-3 antibody; dTK-3 antibody; APTGFTGMR-amide); Tachykinin-associated peptide 3 antibody; TAP3 antibody; Brain peptide PALLAGDDDAEADEATELQQ); Tachykinin-related peptide 4 antibody; TK-4 antibody; dTK-4 antibody; APVNSFVGMR-amide); Tachykinin-associated peptide 4 antibody; TAP4 antibody; Brain peptide DVSHQHY); Tachykinin-associated peptide 5 antibody; TAP5 antibody; AALSDSYDLRGKQQRFADFNSKFVAVR-amide); Tachykinin-associated peptide 6 antibody; TAP6 antibody; Brain peptide SDLEGNGVGIGDDHEQALVHPWLYLWGE); Tachykinin-related peptide 5 antibody; TK-5 antibody; dTK-5 antibody; APNGFLGMR-amide)] antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Tk protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Datasheet & COA

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Target Background

Function(From Uniprot)

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Stimulates gut muscle contractions. Required for the response to the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males. The Gr68a gustatory receptor is required for detection of the pheromone and Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) which leads to courtship suppression through release of tachykinin from a cluster of 8-10 neurons in the SEZ.

Gene References into Functions

These results highlight a conserved role for Tachykinin signaling in regulating nociception. PMID:26575288
Study identified a small group of sexually dimorphic, FruM+ neurons that promote aggressiveness in Drosophila males but have no influence on male-female courtship behavior. These neurons enhance aggression, at least in part, through the release of a neuropeptide, Drosophila tachykinin. PMID:24439378
The control of DILP5 signaling in the renal tubules by Drosophila tachykinin peptide (DTK) and its receptor DTKR during desiccative, nutritional and oxidative stress, was investigated. PMID:21572965
The distribution of the Dtk transcript and peptides was analyzed by in situ hybridization and immunocytochemistry during postembryonic development of the central nervous system (CNS) of Drosophila. PMID:12898611

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Subcellular Location

Secreted.

Protein Families

Tachykinin family

Tissue Specificity

Strong expression is seen in a group of 14 cells plus one isolated cell in the midgut of stage 17 embryos. Also expressed in a pair of medially located unidentified cells, just posterior to the brain, and in two lateral groups of cells that may be associa

Database Links

UNIGENE: Dm.3420

KEGG: dme:Dmel_CG14734

STRING: 7227.FBpp0081962

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