CALHM3 Antibody

Code: CSB-PA768231LA01HU
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Human, Mouse
Raised in: Rabbit
Application: ELISA, WB, IHC, IF
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Product Details

Uniprot NO.
Target Names
CALHM3
Alternative Names
CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Calcium homeostasis modulator protein 3 protein (201-350AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
ApplicationRecommended Dilution
WB1:1000-1:5000
IHC1:20-1:200
IF1:50-1:200
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western Blot
    All lanes: CALHM3 antibody at 8µg/ml + Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 40, 39 kDa
    Observed band size: 40, 55 kDa

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA768231LA01HU at dilution of 1:100

  • Immunofluorescent analysis of U251 cells using CSB-PA768231LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Gene References into Functions
  1. This study failed to show an association between theeight SNPs of the CALHM3 genes and alzheimer disease. PMID:20164573

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Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Protein Families
CALHM family
Tissue Specificity
Specifically expressed in circumvallate taste bud cells.
Database Links

HGNC: 23458

UNIGENE: Hs.364624

KEGG: hsa:119395

STRING: 9606.ENSP00000358798

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