CCNB2 Antibody

Code: CSB-PA004808GA01HU

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Size:

100μl

US$600

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Product Details
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Target Background

Product Details

Uniprot NO.

O95067

Target Names

CCNB2

Alternative Names

ccnb2 antibody; CCNB2_HUMAN antibody; CycB2 antibody; Cyclin B2 antibody; G2 mitotic specific cyclin B2 antibody; G2/mitotic specific cyclin B2 antibody; G2/mitotic-specific cyclin-B2 antibody; HsT17299 antibody; MGC108931 antibody; MGC140694 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human CCNB2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Gene References into Functions

Data show that Islet-1 (ISL1) activated the expression of cyclin B1 (CCNB1), cyclin B2 (CCNB2) and c-myc (c-MYC) genes by binding to the conserved binding sites on their promoters or enhancers. PMID:27183908
Data show that the cyclin B2 was overexpressed in bladder cancer tissue. PMID:26706119
overexpression of CCNB2 protein is associated with clinical progression and poor prognosis in non-small cell lung cancer PMID:26349989
Cyclin B1 and cyclin B2 are interchangeable for ability to promote G2 and M transition in HeLa cells. PMID:24324638
there was no significance in the 5-year overall survival rates among the patients with squamous cell carcinoma between expressing lower and higher level of cyclin B2 mRNA PMID:24375198
Suggest that cytoplasmic CCNB2 may function as an oncogene and could serve as a potential biomarker of unfavorable prognosis over short-term follow-up in breast cancer. PMID:23282137
The relative expression level of circulating CCNB2 mRNA in cancer patients was significantly higher than that in normal controls and benign diseases group. Circulating CCNB2 mRNA level significantly correlated with cancer stage and metastasis status. PMID:21161946
Data suggest that cyclin A2 helps initiate mitosis, in part through its effects on cyclin B1, and that cyclins B1 and B2 are particularly critical for the maintenance of the mitotic state. PMID:20660152
Overexpression of B-type cyclins alters chromosomal segregation PMID:11960377
p300 binds to multiple NF-Y trimers to regulate cyclin B2 promoter function PMID:12482752
cyclin B2 expression in colorectal adenocarcinoma is dependent on NF-Y PMID:17289878
severe reduction by separate RNA interference of either cyclin B1 or cyclin B2 protein levels results in little or no alteration of the cell cycle and, more specifically, of mitosis progression PMID:17533373
This gene may be used as a very reliable biomarker of lung adenocarcinoma. PMID:17549666