Cxcl11 Antibody

Code: CSB-PA09289A0Rb

Rate （5.0）
Review （1）
Citation （1）

Size:

20μg50μg100μg

US$83

Quantity:

Species Reactivity: Mouse

Raised in: Rabbit

Application: ELISA, IHC

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Target Background

Product Details

Uniprot NO.

Q9JHH5

Target Names

Cxcl11

Alternative Names

Cxcl11 antibody; Scyb11C-X-C motif chemokine 11 antibody; Interferon-inducible T-cell alpha chemoattractant antibody; I-TAC antibody; Small-inducible cytokine B11 antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse C-X-C motif chemokine 11 protein (22-98AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA09289A0Rb at dilution of 1:100

Description

The rabbit IgG polyclonal antibody was raised against the recombinant C-X-C motif chemokine 11 protein (22-98aa) expressed in mouse. The rabbit anti-serum collected antibody was affinity purified using Protein G, resulting in a purity of over 95%.

This rabbit anti-mouse Cxcl11 polyclonal antibody is capable of recognizing the mouse Cxcl11 protein and has been validated for use in ELISA and IHC. It can be utilized to detect the presence, quantify the level, or visualize the distribution of Cxcl11 protein in experimental settings.

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

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Applications : Immunofluorescence(IF)

Sample type: Tissue

Review: Representative images of immunofluorescent staining show that the stimulated production of these two chemokines in the corneas and conjunctivas of DS + PBS mice was largely inhibited in DS + 2%Ectoine mice.

By Anonymous

Citations

Ectoine from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease G Frühbeck,/,2024

Target Background

Function(From Uniprot)

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

Gene References into Functions

although the expression of CXCL9 and CXCL11 are increased after spinal nerve ligation, they may not contribute to the maintenance of neuropathic pain. PMID:29712506
These findings functionally integrate K17, hnRNP K, and gene expression along with RSK and CXCR3 signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis PMID:25713416
very low doses of CXCL11 rapidly suppress signs of EAE in C57BL/6 mice lacking functional CXCL11. PMID:24713654
Data indicate that epidermis-derived I-TAC (Cxcl11) triggers a sustained Th2-response that determines the outcome of a complex immunological process. PMID:24398292
Analysis of genes within the Listr1 locus identified a frameshift mutation in the Cxcl11 gene of the C57BL/6 strain that prevents production of the mature chemokine CXCL11. PMID:24566892
Cxcl10 and cxcl11 are new hair-specific transcriptional targets of ectodysplasin, and they indicates involvement of chemokines in hair development. PMID:22277947
the CXCL11-heparin interaction has two different affinities for glycosaminoglycans PMID:20363748
I-TAC can have an important role during virus infections and vaccinia virus has evolved ways to avoid inducing I-TAC expression. PMID:15030574
I-TAC acts as an antagonist for CCR5. I-TAC inhibited the binding of macrophage-inflammatory protein-1alpha (MIP-1alpha)/CC chemokine ligand 3 (CCL3) to cells transfected with CCR5 and to monocytes. PMID:15178708
Acute ethanol intoxication impairs lung expression of Cxcl11, interfering with pulmonary response to bacterial challenge. PMID:17889309
homologous to human T cell attracting chemokine CXC receptor ligand 11; involved in calcium mobilization and chemotaxis PMID:11500837