EMP3 Antibody

Code: CSB-PA007650LA01HU

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20μg50μg100μg

US$83

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Species Reactivity: Human, Mouse

Raised in: Rabbit

Application: ELISA, WB, IF

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Target Background

Product Details

Uniprot NO.

P54852

Target Names

EMP3

Alternative Names

EMP3; YMP; Epithelial membrane protein 3; EMP-3; Hematopoietic neural membrane protein 1; HNMP-1; Protein YMP

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Epithelial membrane protein 3 protein (25-65AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IF	1:50-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunofluorescent analysis of Hela cells using CSB-PA007650LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Western Blot
All lanes: EMP3 antibody at 3µg/ml + Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 19 kDa
Observed band size: 19, 31 kDa

Description

The EMP3 polyclonal antibody was generated in rabbits using recombinant human EMP3 protein (25-65aa) as the immunogen and purified to a level greater than 95% using protein G affinity chromatography. This liquid-form antibody has been tested and proven reactive with human and mouse samples, making it suitable for use in a variety of experimental contexts.

Additionally, this EMP3 polyclonal antibody has been tested in ELISA and WB and has demonstrated its efficacy in recognizing and binding to EMP3 protein. The EMP3 polyclonal antibody's function includes the ability to detect, evaluate, and quantify EMP3 protein levels in biological samples.

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Target Background

Function(From Uniprot)

Probably involved in cell proliferation and cell-cell interactions.

Gene References into Functions

This study identified and validated a three-gene (EMP3, GSX2 and EMILIN3) prognostic signature in Lower-Grade Gliomas. PMID:29794476
High EMP3 expression is associated with high grade glioma. PMID:27527869
epithelial membrane protein 3 is a downstream effector of TWIST1/2 in inducing epithelial-to-mesenchymal transition in gastric cancer. Epithelial membrane protein 3 upregulation might be associated with gastric cancer metastasis and is a potential indicator of unfavorable overall survival and progression-free survival in gastric cancer patients PMID:28718375
Independent validation with glioma patients tissue (n = 70) and normal brain tissue (n = 19) found PPIC, EMP3 and CHI3L1 were up-regulated in glioma tissue. Survival value validation showed that the three genes correlated with patient survival by Kaplan-Meir analysis, including grades, age and therapy. PMID:27801851
The study provided a new insight into EMP3, suggesting that EMP3 enhances malignancy of hepatocellular carcinoma cells PMID:26472188
EMP3 functions as an oncogene and is regulated by microRNA-765 in primary breast carcinoma. PMID:26398721
The aim of this study was to investigate the EMP3 promoter hypermethylation status in a series of 229 astrocytic and oligodendroglial tumors and in 16 glioblastoma cell lines. PMID:24083241
Decreased expression of EMP3 by promoter methylation is associated by lung cancer PMID:23920144
LOH 19q determines the complete loss of EMP3 function, as the conserved allele is frequently hypermethylated, and this may represent the molecular basis of the higher risk of relapse in this subgroup of grade II oligodendroglioma patients. PMID:22992787
The promoter methylation and mRNA expressions of EMP3 and PCDH-gamma-A11 are closely related with the malignant development of glioma. PMID:20388442
EMP3 overexpression is associated with oligodendroglial tumors PMID:17187361
Oligodendroglial and astrocytic gliomas show EMP3 hypermethylation and aberrant expression. Primary and secondary glioblastomas have distinct genetic profiles and also differ in their epigenetic aberrations. PMID:17610521
Loss of EMP3 is associated with esophageal squamous cell carcinoma. PMID:18823699
Epithelial membrane protein 3 overexpression in breast carcinomas was significantly related to histological grade III , lymph node metastasis , and strong Her-2 expression. PMID:19270820