GNAZ Antibody

Code: CSB-PA796881

Rate （N/A）
Review （0）

Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,IHC

Send an Inquiry

Start an on-line Chat

Online ordering is currently available for U.S. customers only. For orders outside the U.S., please kindly submit an inquiry or start a chat with us.

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot NO.

P19086

Target Names

GNAZ

Alternative Names

G(x) alpha chain antibody; GNAZ antibody; GNAZ_HUMAN antibody; Guanine nucleotide-binding protein G(z) subunit alpha antibody; Gz-alpha antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human GNAZ

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Tested Applications

ELISA,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA796881(GNAZ Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA796881(GNAZ Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Gene References into Functions

GNAZ mutations are associated with melanoma. PMID:20424519
cGMP-phosphodiesterase 6 can be activated by another cancer-retina antigen, transducin, through Wnt5a-Frizzled-2 cascade, which leads to a lowering of cGMP and an increase in intracellular calcium mobilization. PMID:19946729
findings suggest that Galphaz signals may attenuate Rho-induced stimulation of SRF-mediated transcription PMID:15326221

Hide All

Subcellular Location

Membrane; Lipid-anchor.

Protein Families

G-alpha family, G(i/o/t/z) subfamily

Database Links

HGNC: 4395

UNIGENE: Hs.584760

KEGG: hsa:2781

STRING: 9606.ENSP00000248996

OMIM: 139160

Promotions