MC5R Antibody

Code: CSB-PA067089

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Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,IHC

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Product Details
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Target Background

Product Details

Uniprot NO.

P33032

Target Names

MC5R

Alternative Names

MC5R; Melanocortin receptor 5; MC5-R; MC-2

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human MC5R

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Tested Applications

ELISA,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA067089(MC5R Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

Gene References into Functions

Mutations in residues S4/S5 and S17/E18 retained MC5R at the ER/Golgi complex and did not affect MC5R homodimerization. PMID:28396017
D115 and D119 in TM3, F195 in TM5, and F254 in TM6 may form a binding pocket for NDP-alpha-MSH binding. PMID:23414113
Melanocortin 5 receptor signaling and internalization: role of MAPK/ERK pathway and beta-arrestins 1/2. PMID:22871966
Variations in the melanocortin 5 receptor gene are unlikely to confer susceptibility to bipolar disorder in this sample. PMID:16314755
Further structure-activity studies of lactam derivatives of MT-II and SHU-9119 were made at MC5R. PMID:17482720
MC5R signals through a PI3K-regulated Akt-independent pathway leading to downstream activation of ERK1/2 PMID:19428994