MRGPRX3 Antibody

Code: CSB-PA850382LA01HU

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20μg50μg100μg

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, IF

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Target Background

Product Details

Uniprot NO.

Q96LB0

Target Names

MRGPRX3

Alternative Names

G protein coupled receptor SNSR1 antibody; G protein coupled receptor SNSR2 antibody; G protein-coupled receptor MRGX 3 antibody; G protein-coupled receptor MRGX3 antibody; GPCR antibody; Mas related GPCR member X3 antibody; Mas-related G protein coupled MRGX 3 antibody; Mas-related G protein coupled MRGX3 antibody; Mas-related G-protein coupled receptor member X3 antibody; MAS-related GPR, member X3 antibody; MRGPRX3 antibody; MRGX3 antibody; MRGX3_HUMAN antibody; Sensory neuron-specific G-protein coupled receptor 1 antibody; Sensory neuron-specific G-protein coupled receptor 1/2 antibody; SNSR1 antibody; SNSR2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Mas-related G-protein coupled receptor member X3 protein (276-322AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunofluorescent analysis of HepG2 cells using CSB-PA850382LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Target Background

Function(From Uniprot)

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.

Gene References into Functions

Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID:29408502
Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID:28189739
overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID:15809047

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family, Mas subfamily

Tissue Specificity

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Database Links

HGNC: 17980

UNIGENE: Hs.380177

KEGG: hsa:117195

STRING: 9606.ENSP00000379571