SECTM1 Antibody

Code: CSB-PA819898LA01HU

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US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, IHC, IF

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Target Background

Product Details

Uniprot NO.

Q8WVN6

Target Names

SECTM1

Alternative Names

SECTM1 antibody; K12 antibody; Secreted and transmembrane protein 1 antibody; Protein K-12 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Secreted and transmembrane protein 1 protein (29-145AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA819898LA01HU at dilution of 1:100
Immunofluorescent analysis of PC-3 cells cells using CSB-PA819898LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Target Background

Function(From Uniprot)

May be involved in thymocyte signaling.

Gene References into Functions

CD7 is present on monocytes and tumor macrophages and its ligand, SECTM1, is frequently expressed in corresponding melanoma tissues PMID:24157461
SECTM1 secreted from bone marrow stromal cells may interact with CD7 to influence GM-CSF expression in leukemic cells. PMID:24211252
level of SECTM1 expression is likely to be a key factor in innate immune responses and in the immune tolerance of cancerous cells PMID:21749909

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Subcellular Location

Cell membrane; Single-pass type I membrane protein. Secreted.

Protein Families

SECTM family

Tissue Specificity

Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic

Database Links

HGNC: 10707

UNIGENE: Hs.558009

KEGG: hsa:6398

STRING: 9606.ENSP00000269389

OMIM: 602602

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