SSTR3 Antibody

Code: CSB-PA597067

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Size:

50μl100μl

US$166

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,IHC

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Target Background

Product Details

Uniprot NO.

P32745

Target Names

SSTR3

Alternative Names

SSTR3; Somatostatin receptor type 3; SS-3-R; SS3-R; SS3R; SSR-28

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human SSTR3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Tested Applications

ELISA,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA597067(SSTR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA597067(SSTR3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

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Target Background

Function(From Uniprot)

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

Gene References into Functions

the C-terminal phosphorylation motif of the human sst3 receptor that regulates its agonist-promoted phosphorylation, beta-arrestin recruitment, and internalization of this clinically relevant receptor, is reported. PMID:27101376
findings provide new insights in understanding the antiproliferative role of SSTR3 in breast tumor biology. PMID:26112183
In conclusions, in CNFAs, high expression of somatostatin receptors is much less common than that of D2R PMID:25536318
constitutive SSTR3 activity mediates transcriptional repression of GH. PMID:24606125
High SSTR3 expression is associated with gallbladder cancer. PMID:23991955
Determination of the expression of SSTR3 in an attempt to establish correlations and/or associations with clinical characteristics of patients with nonfunctioning pituitary adenomas. PMID:22419713
mRNA levels of SSTR2a, SSTR3 and SSTR5 in neuroendocrine lung cancer affected patients, were determined PMID:21503779
The cigarettes smoking and H. pylori infection are independent factors leading to decreasing of the SSTR3 mRNA level in gastric mucosa of patients with functional dyspepsia. PMID:20570798
There was a positive correlation between the percentage of tumor reduction by octreotide-lar and SSTR3 expression. PMID:19330452
expression of somatostatin (SS) and SS receptor (SSR) subtype 1 (sst1), sst2A, and sst3 in normal human thymic tissue PMID:12376335
localization and expression in human prostatic tissue and prostate cancer cell lines. PMID:12474541
Reduced SSTR3 expression is associated with gastric cancers PMID:15197339
Density of the SSTR3 receptor is decreased in gastric adenocarcinoma. H. pylori infection related reduction of the SSTR3 density in the antrum mucosa speaks for the need of eradication of these bacteria in the prevention of distal gastric cancer. PMID:17679363
Determine the influence of H. pylori infection and a family history of gastric cancer on the expression of SSTR3 in the gastric mucosa of non-cancer patients with dyspepsia. PMID:17683502
There was very little expression of SSTR3 in benign, premalignant, and cancerous laryngeal specimens; thus SSTR3 does not have an important role in laryngeal patholgy. PMID:18066572
Immunohistochemistry stufy of SSTR3 in prostate tissue from patients with bladder outlet obstruction showed that greatest proportion of basal cells showed a moderate intensity, strong immunoreactivity being observed only in 15.8% of cells. PMID:18936524
An interaction between the human somatostatin receptor 3 and the multiple PDZ protein MUPP1 was identified. PMID:19071123