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Recombinant Bovine Estrogen receptor beta (ESR2), partial

Recombinant Bovine Estrogen receptor beta (ESR2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

ESR2

Purity

>85% (SDS-PAGE)

Target Names

ESR2

Uniprot NO.

Q9XSB5

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-527

Target Protein Sequence

MDVKNSPSSL NSPVSYNCGQ SILPLEPGPI YLPSSYVESR HEYSAVTFYS PAVMNYSIPN NSEDGPGRQT TSPNVLWPTP GHLSPLAIHC QPSVLYAEPQ KSPWRETRSL EHTLPVNRET LKRKASGSSC ASPATSPSSK RDAHFCAVCS DYASGYHYGV WSCEGCKAFF KRSIQGHNDY ICPATNQCTI DKNRRKSCQA CRLRKCYEVG MVKCGSRRER CGYRIVRRQR NSDEQLHCLS KTKRNGGPMT RVKELLLSAL SPEQLVLTLL EAEPPHVLIS RPSTPFTEAS MMMSLTKLAD KELVHMISWA KKIPGFVELS LYDQVRLLES CWLEVLMVGL MWRSIDHPGK LIFAPDLILD RDEGKCVEGI LEIFDMLLAT TSRFRELKLQ HKEYLCVKAM ILLNSSMYPS ATAPQEADSG RKLTHLLNAV TDALVWVIAK SGMSSQQQSM RLANLLMLLS HVRHASNKGM EHLLNMKCKN VVPVYDLLLE MLNAHTLRGN KSLVTGSERN LVEDSESKEG SQKPQAQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.

Gene References into Functions

The mRNA expression of ER-alpha and ER-beta in the hypothalamus of developing male and female bovines, is reported. PMID:25363750
ER-alpha is detected predominantly in the soma whereas ER-beta is only present in the nucleus of a few cells in the frontal cortex. PMID:21397601
fetal ovary of cattle has the steroidogenic enzyme aromatase to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary PMID:19299095
there are different levels of ERalpha, ERbeta and PR in bovine oviducts at different cycle stages in vivo PMID:12711014
ER may play a role in the rapid effects of resveratrol in EC and some of the atheroprotective effects of resveratrol may be mediated through rapid activation of ER signaling in EC PMID:15615701
The expression of estrogen and progesterone receptors in ovarian follicular structures from cows with cystic ovarian disease (COD) and a comparison of these with normal ovarian structures are reported. PMID:17491080
These data indicate that PGF2alpha, TNFalpha and IFNgamma regulate ERalpha and ERbeta mRNA expressions in bovine luteal cells. PMID:17598955
Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells. PMID:18403176