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Recombinant Chicken Histone deacetylase 4 (HDAC4), partial

Recombinant Chicken Histone deacetylase 4 (HDAC4), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

HDAC4

Uniprot NO.

P83038

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-1080

Target Protein Sequence

MSSQSHPDGL SGRDQPVELL NPPRVNHMPS SVDVSTALPL QVAPTSVPMD LRLDHQFPMP VTEPTLREQQ LQQELLALKQ KQQIQRQILI AEFQRQHEQL SRQHEAQLHE HIKQQEMLAM KHQQELLEHQ RKLEQHRQEQ ELEKQHREQK LQQLKNKEKG KESAVASTEV KMKLQEFVLN KKKALAHRNL NHCISSDPRF WYGKTQHSSL DQSSPPQSGV SGTYNHPVLG MYDSKDDFPL RKTASEPNLK LRSRLKQKVA ERRSSPLLRR KDGPVVTALK KRPLDVTDSA CNSAPGSGPS SPNNSSNNIS AENGITGSVT SIQAETSLAH RLVNREGSVT QLPLYTSPSL PNITLGLPAT GPSSGGSAQQ DAERLAIPAL QQRISLFPGT HLTPYLSTTT LERDGGTAHN PLLQHMVLLE QPTAQTPLVT GLPLHAQSLV GGERVSPSIH KLRQHRPLGR TQSAPLPQNA QALQQLVIQQ QHQQFLEKHK QQFQQQQLHI NKIISKPNEP ARQHESHPEE TEEELREHQA LLEEPYSDRV SSQKEVPGLA NMVQVKQEPI ESDEEEAEPQ QELESGQRQA EQELLFRQQA LLLEQQRIHQ LRNYQASLEA AGMPVSFGGH RPLSRAQSSP ASATFPMSVQ EPPTKPRFTT GLVYDTLMLK HQCTCGNTNS HPEHAGRIQS IWSRLQETGL RGKCECIRGR KATLEELQTV HSEAHTLLYG TNPLNRQKLD SKKLLGSLTS MFVRLPCGGV GVDSDTIWNE VHSSGAARLA VGCVIELVFK VATGELKNGF AVVRPPGHHA EESTPMGFCY FNSVAIAAKL LQQRLNVSKI LIVDWDVHHG NGTQQAFYND PNVLYISLHR YDDGNFFPGS GAPDEVGTGA GVGFNVNMAF TGGLDPPMGD TEYLTAFRTV VMPIANEFAP DVVLVSSGFD AVEGHPTPLG GYNLSAKCFG YLTKQLMGLA GGRVVLALEG GHDLTAICDA SEACVSALLG NELDPLPEKV LQQRANANAV HSMEKVIEIH SKYWHSLQRY ASTVGYSLVE AQKCENEEAE TVTAMASLSV GVKPAEKRPD DEPMEEEPPL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Gene References into Functions

findings indicate that HDAC4 nuclear-cytoplasmic shuttling controls chondrocyte differentiation in the growth plate, which is dependent on the Ca2 /calmodulin signaling pathway PMID:22442139

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Subcellular Location

Nucleus.

Protein Families

Histone deacetylase family, HD type 2 subfamily

Database Links

UNIGENE: Gga.3689

KEGG: gga:374207

STRING: 9031.ENSGALP00000006811

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