Recombinant Rat Transcription factor jun-D (Jund)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Jund

Uniprot NO.

P52909

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-341

Target Protein Sequence

METPFYGEEA LSGLAAGASS VAGAAGAPGG GGFAPPGRAF PGAPPTSSML KKDALTLSLA EQGAAGLKPG SATAPSALRP DGAPDGLLAS PDLGLLKLAS PELERLIIQS NGLVTTTPTS TQFLYPKVAA SEEQEFAEGF VKALEDLHKQ SQLGAATAAT SGAPAPPAPA DLAATPGATE TPVYANLSSF AGGAGPPGGA ATVAFAAEPV PFPPPPGALG PPPPPHPPRL AALKDEPQTV PDVPSFGDSP PLSPIDMDTQ ERIKAERKRL RNRIAASKCR KRKLERISRL EEKVKTLKSQ NTELASTASL LREQVAQLKQ KVLSHVNSGC QLLPQHQVPA Y
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcription factor binding AP-1 sites.

Gene References into Functions

JunD activates miR-29b by enhancing its transcription and processing, which contribute to the inhibitory effect of JunD PMID:25788572
JunD is highly co-expressed with c-Fos in magnocellular neurons of the supraoptic nucleus following dehydration. PMID:22827527
These results indicate that induced ATF-2/JunD association following polyamine depletion represses CDK4 transcription, thus contributing to the inhibition of intestinal epithelial cell growth. PMID:20181929
Translation initiation from alternative AUG and non-AUG sites in human, mouse and rat. PMID:12105216
JunD bound to the proximal region of the CDK4-promoter in vitro as well as in vivo. transcriptional repression of CDK4 by JunD was mediated through an AP-1 binding site within this proximal sequence of the CDK4-promoter. PMID:17253961
JunD is a major determinant of macrophage activity and is associated with glomerulonephritis susceptibility. PMID:18443593