Recombinant Sheep Renin (REN)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

REN

Uniprot NO.

P52115

Species

Ovis aries (Sheep)

Source

Yeast

Expression Region

60-400

Target Protein Sequence

T LSFGNRTSPV VLTNYLDTQY YGEIGIGTPP QTFKVIFDTG SANLWVPSTK CSPLYTACEI HSLYDSLESS SYVENGTEFT IYYGSGKVKG FLSQDLVTVG GITVTQTFGE VTELPLRPFM LAKFDGVLGM GFPAQAVGGV TPVFDHILAQ RVLTEDVFSV YYSRDSKNSH LLGGEIVLGG SDPQYYQENF HYVSISKPGS WQIRMKGVSV RSTTLLCEEG CMVVVDTGAS YISGPTSSLR LLMEALGAKE LSIDEYVVNC NQMPTLPDIS FHLGGKAYTL TSADYVLQDP YNNISCTLAL HGMDIPPPTG PVWVLGATFI RKFYTEFDRR NNRIGFALAR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

Gene References into Functions

replacement of thyroid hormone in hypothyroid sheep fetuses can restore renal ANG II receptor and renin expression and secretion to normal PMID:17567715

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Subcellular Location

Secreted. Membrane.

Protein Families

Peptidase A1 family

Tissue Specificity

Kidney.

Database Links

UNIGENE: Oar.403

KEGG: oas:443310

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