CT26/Human GPRC5D Stable Cell Line

Code: CSB-SC882153HU1

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Size:

1 vial contains approximately 5x10⁶ cells in 1 ml

US$5000

Quantity:

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Target Background

Product Details

Growth Properties

Adherent

Selection Marker

Puromycin

Culture Medium

RPMI 1640 + 10% FBS + 8 μg/mL Puromycin

Tag Info

Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Buffer

35% FBS + 55% RPMI 1640 + 10% DMSO

Storage

Frozen in liquid nitrogen or -80°C

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Images

Untransfected CT26 cells (green line) and transfected Human GPRC5D CT26 stable cells (red line) were stained with anti-GPRC5D antibody(CSB-RA882153MA01HU) (2µg/1*10⁶cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

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Target Background

Gene References into Functions

GPRC5D in MM cells makes this gene and its encoded surface protein as promising markers for monitoring the tumor load and hopefully also as targets for antimyeloma antibodies. PMID:23510526
Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma. PMID:22591013

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 3 family

Tissue Specificity

Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscl

Database Links

HGNC: 13310

UNIGENE: Hs.644599

KEGG: hsa:55507

STRING: 9606.ENSP00000228887

OMIM: 607437

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