MC38/Human CLDN9 Stable Cell Line

Code: CSB-SC005511HU2

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Size:

1 vial contains approximately 5x10⁶ cells in 1 ml

US$5000

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Target Background

Product Details

Growth Properties

Adherent

Selection Marker

Puromycin

Culture Medium

DMEM + 10% FBS + 4 μg/ml Puromycin

Tag Info

Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Buffer

35% FBS + 55% DMEM + 10% DMSO

Storage

Frozen in liquid nitrogen or -80°C

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Images

Untransfected MC38 cells (green line) and transfected Human CLDN9 MC38 stable cells (red line) were stained with anti-CLDN6/9 antibody (CSB-RA005508MA1HU) (2µg/1*10⁶cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

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Target Background

Function(From Uniprot)

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.; (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.

Gene References into Functions

CLDN9 may be an important biomarker for invasive pituitary oncocytomas. PMID:25281028
Claudins 6, 7, and 9 expressions are closely related to gastric carcinogenesis. PMID:19960275
Mouse studies suggest that claudin-9 deficiency may cause hearing loss not only in mice but also in humans. PMID:19696885
Residues N38 and V45 in the first extracellular loop (EL1) of CLDN9 are necessary for HCV entry. PMID:17804490
CLDN9, clustered with CLDN6 at human chromosome 16p13.3, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. PMID:12736707